of poison control centers


Poison control centers began receiving calls about e-cigarettes and liquid nicotine products in 2011, which coincides with the initial period where these products reached the U.S. market. These products often contain a greater concentration of nicotine, a stimulant, than other nicotine/tobacco products on the market. Some children and toddlers who come in contact with e-cigarette devices or liquid nicotine have become very ill; some even requiring emergency department visits with nausea and vomiting being the most significant symptoms.

As of August 31, 2022, poison control centers have managed 4,197 exposure cases about e-cigarette devices and liquid nicotine in 2022. For more information on how poison control center data is collected, please click here.


Please cite this data as “National Poison Data System, American Association of Poison Control Centers.” Any and all print, digital, social, or visual media using this data must include the: “You can reach your local poison control center by calling the Poison Help hotline: 1-800-222-1222. To save the number in your mobile phone, text POISON to 301-597-7137.” Email or call 703-894-1863 for more information, questions, or to submit request data.



  1. Protect your skin when handling the products.

  2. Take special care to always keep any nicotine-containing product, including e-cigarettes and liquid nicotine, out of the reach of children.

  3. Follow the specific disposal instructions on the label.

  4. If you think someone has been exposed in a dangerous way to an e-cigarette or liquid nicotine, call the Poison Help hotline at 1-800-222-1222 immediately.


For more safety information, visit the E-Cigarette and Liquid Nicotine Exposures prevention page.


Important notes about poison control center data

AAPCC maintains the National Poison Data System (NPDS) , the national database of information logged by the country’s regional poison control centers serving all 50 United States, Puerto Rico, the District of Columbia, and territories. Case records in this database are from self-reported calls: they reflect only information provided when the public or healthcare professionals report an actual or potential exposure to a substance, request information, or request educational materials. As such:
  • AAPCC is not able to completely verify the accuracy of every report made to member centers.
  • Additional exposures may go unreported to poison control centers and data referenced from the AAPCC should not be construed to represent the complete incidence of national exposures to any substance(s).
  • Poison control call volume about any given substance is influenced by the public’s awareness of the hazard or even the Poison Help hotline itself, which are heavily influenced by both social and traditional media coverage.
  • Poison control data are considered preliminary and are subject to change until the dataset for a given year has been locked.
  • AAPCC is continuously working to update the NPDS substance coding taxonomy to better serve the needs of AAPCC members and surveillance partners. As a result, substances may be reclassified within NPDS’ coding hierarchy, and case counts may change. This is particularly true for novel or emerging substances.

The term “exposure” means someone has had contact with the substance in some way; for example, ingested, inhaled, or absorbed a substance by the skin or eyes, etc. Exposures do not necessarily represent poisonings or overdoses.


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